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Gamblecode > Blog > News & Trends > Oklahoma State vs Houston Betting Odds Preview

Oklahoma State vs Houston Betting Odds Preview

The team By The team 7 October 2025 3 Min Read
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Oklahoma State vs Houston Betting Odds Preview
An Oklahoma State helmet is pictured before a college football game between the Oklahoma State Cowboys (OSU) and the West Virginia Mountaineers at Boone Pickens Stadium in Stillwater, Okla., Saturday, Oct. 5, 2024. / BRYAN TERRY/THE OKLAHOMAN / USA TODAY NETWORK via Imagn Images

Introduction to the Big 12 Battle

Oklahoma State is gearing up for another intense Big 12 battle, this time as a significant underdog. On Saturday, the team will host Houston in its third Big 12 game of the season, aiming to break its 13-game FBS losing streak. The Cougars, looking to bounce back from their loss to Texas Tech, are expected to give the Pokes a tough time on Saturday.

Contents
Introduction to the Big 12 BattleThe Betting OddsTeam PerformanceQuarterback ChallengesPossibility of an UpsetConclusion

The Betting Odds

The Cowboys are once again entering a game as multiple-touchdown underdogs. Staying within two scores of the Cougars could be a challenge, considering the team’s lack of success this season. With everything that has happened in the past couple of weeks, being a two-touchdown underdog at home seems like a win for the program. However, covering this spread could be a big-time challenge.

Team Performance

This season, OSU has a season-high of 27 points, while Houston has a season-high of 36. The 46.5-point over/under for OSU-Houston seems like a hard line to hit, considering both teams’ resumes. Houston’s defense, although not the best OSU has faced, ranks in the top half of the NCAA in major defensive stats, including a top-30 spot in points allowed and a top-35 spot in passing defense.

Quarterback Challenges

OSU will kick off Saturday with a third starting quarterback, which could impact the team’s performance. The Cougars’ ability to put up points against a depleted Cowboy defense will likely determine the outcome of the game. Seeing OSU with relatively decent odds of getting a win is a welcome sight after the past few weeks. However, an unranked Houston team coming into Stillwater with a moneyline of -750 isn’t a great sign for the state of the program.

Possibility of an Upset

The idea of an OSU upset win feels more realistic in this game than in their other two Big 12 contests. The Cougars’ rough outing against Texas Tech could have been a turning point ahead of their trip to Stillwater. Although the odds are against them, the Cowboys might have a chance to surprise their opponents.

Conclusion

In conclusion, Oklahoma State faces an uphill battle against Houston in their upcoming Big 12 game. While the odds are against them, the team has a chance to break their losing streak and pull off an upset. With the right strategy and performance, the Cowboys might be able to stay within two scores of the Cougars or even secure a win. As the game approaches, fans will be watching closely to see how the team performs under their new quarterback and whether they can turn their season around.

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